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later complications include dyspnoea, pneumonia, respiratory failure and sepsis (a state where an infection from a micro-organism spreads throughout the body, causing an overwhelming inflammatory response, multi-organ damage and shock), which can be fatal (7)

The combined group had a significantly lower risk of all-cause mortality than SGLT2i monotherapy (aHR = 0.53) and GLP-1RAs monotherapy (aHR = 0.43) after a mean follow-up of 2.4 years

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Temporal Changes in SGLT2 Inhibitor and GLP-1 Receptor Agonist Use in Patients with Chronic Kidney Disease and Type 2 Diabetes, 20122023: A US Cohort Study