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The aqueous phase was collected until the organic phase was clarified, and then the aqueous phase was evaporated at 49 C to remove residual organic solvents

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Acute SNIP1 depletion disrupts RES incorporation, causes widespread splicing defects, and promotes hyperphosphorylation of SF3B1 by CDK11

Once the drug solution starts to perfuse into the tissue, it preferentially passes along the intercellular area in the tissues which have a typical alignment pattern (Fig