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Gastrointestinal Reactions (Reported/Theoretical) : Some reports suggest possible nausea or digestive discomfort, although consistent human data are lacking

Use of genetically manipulated strains of Clostridium perfringens reveals that both alpha-toxin and theta-toxin are required for vascular leukostasis to occur in experimental gas gangrene

Initial correction of significant deficiency typically involves weekly or biweekly injections for several weeks until levels normalize and symptoms resolve