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For instance, the participants mean score of MMSE was very low (16.5) and the subjects had cognitive impairment, 21 whereas in this study, the mean score of MMSE, which was very high (27), indicated a normal cognitive function

92 Phosphorylation and activation of AMPK is in response to nutrients and AMP/ATP ratio through the upstream kinases serine/threonine kinase (LKB1) and calcium/calmodulin-dependent protein kinase (CaMKK)