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Lipase can also affect local pancreatic blood flow and induce edema, contributing to further tissue necrosis and exacerbating the pathology ( Furthermore, it is crucial to explore the relationship between lipase activation and inflammatory pathways beyond necrosome formation, specifically the interaction with the NLRP3 inflammasome ( Additionally, the buildup of fatty acids is a significant pathological phenomenon in AP
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Consequently, the observed reduction in MDA levels following AOX therapy highlights its therapeutic significance in alleviating OS and improving outcomes in OS-related male infertility
Proc Natl Acad Sci (2008) 105:13216
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