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Electrolytes: On days when hydration is difficult or when you experience diarrhea (reported in about 24% of participants at the 12 mg dose), an electrolyte supplement or low sugar electrolyte drink can prevent mineral depletion
For a deeper understanding of how tirzepatide interacts with various B12 formulations, our guide on tirzepatide glycine B12 compounds covers the science in detail
This results in modest reductions in hemoglobin A1c (HbA1c), body weight, and systolic blood pressure, largely mediated through osmotic diuresis and natriuresis [19]
Graaf CD, Donnelly D, Wootten D, et al
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