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[5] Use of Lipo-C Injection is contraindicated in patients with known hypersensitivity to methionine, choline salts, carnitine, dexpanthenol, or any formulation excipients, as well as in individuals with severe hepatic failure in whom augmented methionine intake could precipitate hypermethioninemia and encephalopathy

Blunted or impeded therapeutic response to vitamin B12 may be due to such conditions as infection, uremia, drugs having bone marrow suppressant properties such as chloramphenicol, and concurrent iron or folic acid deficiency

Nature Reviews Disease Primers , 4(1), 1-25

[DOI] [PubMed] [Google Scholar] 152.Sikiric P., Crvenkovic D., Sever M., Lojo N., Krstonijevic Z., Drmic D., Zenko A., Brcic L., Zoricic I., Rasic Z., et al