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Additional oral supplementation with polypodium leucotomos extract (PLE) at 480 mg twice daily can be helpful (anecdotal evidence, unpublished)

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According to Hartenstein and Giangrande (2018), astrocytes and oligodendrocytes are neuroectodermally derived lineages that are absent in prebilaterian animals (such as Cnidaria and Ctenophora) and in basal branches of the Bilateria