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There were no major adverse reactions reported, with the most common side effects being headache and facial asymmetry

[12] Clinical manifestations, such as low blood pressure, and low-grade fevers, and dark circles around the eyes, may occur

Specifically, mTG is included in numerous meat products and possesses emulsifying properties known to increase intestinal permeability as previously described (Kaufmann et al

Bioavailability limitations require 2-3x higher doses for nasal versus injectable delivery , creating corresponding 2-3x cost increases that make nasal spray primarily appropriate for needle-phobic individuals or peptides specifically designed for nasal use