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This stability eliminates the need for protective carriers that other growth factors require

The bioavailability difference between the two routes compounds the distinction: topical application creates a localized skin depot, while injection delivers the peptide systemically at concentrations impossible to achieve through the skin barrier

In animal research it promotes cell migration, soft-tissue and muscle regeneration, and new blood-vessel formation

Toxic substances in cigarette smoke have the potential to increase free radicals, malondialdehyde (MDA) levels and to decrease endogenous antioxidant (glutathione/GSH) levels