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Certain individuals should not receive B12 injections without explicit medical clearance or should avoid them altogether

A review of 38 RCTs comprising 7,551 patients on ICI therapy evaluated the incidence of endocrine irAEs and found a higher incidence of hypo and hyperthyroidism, especially in patients receiving combined ICI therapy (OR: 3.81

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References Shreya D, Fish PN, Du D