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Novelty The established literature widely acknowledges GHK-Cus regenerative capacity in skin and systemic wound healing

The plant has also been associated with hypocholesterolemic, hypoglycemic, and BP-lowering effects (342), and its antiproliferative and hepatoprotective properties are used medicinally (338)

A 20-nucleotide segment before NGG in the exon of LtGPX3 was selected, and amplified using primers modified with sticky ends (5 end) for single-guide RNA (sgRNA), which was inserted into the linearized pmCas9 vector (Fig