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The primary endpoint was the reduction in the percentage of heavy drinking days (HDD) over 26 weeks, with an HDD defined as the consumption of 60 grams or more of alcohol per day for men, or 48 grams or more of alcohol per day for women (one alcoholic drink typically contains 14 grams of pure alcohol)

Metabolite identification was performed according to the methods described by Fiehn

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Androgen receptor (AR) promotes male bladder cancer cell proliferation and migration via regulating CD24 and VEGF