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It also stimulates collagen and elastin synthesis through fibroblast activation, and its copper-chelating properties contribute to antioxidant defense by modulating copper-dependent superoxide dismutase activity

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These small vesicles plays a major role in the formation of pre-metastatic niche by modifying distant organs (brain, liver, lung, etc.) and enhancing metastatic organotropism (124)

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Deficiency is linked to poor sleep quality, shorter sleep duration, and increased daytime sleepiness

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