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Pushing beyond it isn't just risky

Impaired individuals exhibit hypomethylation of CpG sites in the CCL11 promoter region, which are then hypermethylated upon supplementation with B12 In impaired individuals, three CpG sites exhibited hypomethylation when compared to the non-impaired group

This allows the vitamin to be absorbed more effectively than through the digestive system, making it ideal for those with dietary limitations or absorption issues