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On January 17, 2025, the EMA also started a review on the potential association between semaglutide and non-arteritic anterior ischemic optic neuropathy [148]

The predicted LogP values were calculated as 4.971 (Molinspiration) and 3.23 (Cambridgesoft), while the predicted pKa values were 1.94, 3.74, and 9.22 (Marvin), as well as 2.118, 3.632, and 9.369 (Cambridgesoft)

Similarly, ferrostain-1, a specific inhibitor of ferroptosis, was found to attenuate cognitive impairment in epileptic rats by inhibiting P38 mitogen-activated protein kinase activation (Ye et al., 2020)

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