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Recommended injection sites: Abdomen (at least 2 inches from the navel) Front of the thighs Outer area of the upper arms (if assisted) Rotate injection sites weekly to minimize irritation and improve absorption

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10,11,81,82 Specifically, TLR-2, TLR-4, and the myeloid differentiation primary response protein 88 (MyD88) are crucial to the inflammatory reaction of macrophages to uric acid crystals