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Liraglutide shows dose-dependent nausea ratesVictoza (for diabetes) has rates around 10-17% depending on dose, while Saxenda (3.0 mg for weight management) has significantly higher nausea rates of approximately 39% according to its SmPC

Research suggests it works about as well as the injection and could be a welcome option for anyone who prefers a pill over a needle

Going slow can be a powerful way to reduce nausea and other digestive side effects, which usually resolve as your body adjusts

The SURMOUNT-1 trial (N=2,539), published in the New England Journal of Medicine in 2022 (DOI: 10.1056/NEJMoa2206038), evaluated tirzepatide at 5mg, 10mg, and 15mg weekly doses versus placebo in adults with obesity or overweight