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l-Carnitine protects C2C12 cells against mitochondrial superoxide overproduction and cell death

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To build the R615C pig RyR1 open structure in complex with atorvastatin, we used the open rabbit RyR1:atorvastatin complex, modified by the program MODELER 55 to update pig-specific side chains, followed by rigid body refinement and several rounds of PHENIX real space refinement and ISOLDE

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Benkhoucha M, Molnarfi N, Kaya G, Belnoue E, Bjarnadttir K, Dietrich P-Y, Walker PR, Martinvalet D, Derouazi M, Lalive PH

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NIH 2013

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