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One of the major conclusions of (4, p13) is that The global health and economic burden of tobacco use is enormous and is being increasingly born by low and middle income countries

A decrease in drug metabolism is shown in vapes containing flavouring agents such as benzaldehyde and cinnamaldehyde that are potent inhibitors of the CYP2A6 enzyme, which is primarily responsible for the metabolism of nicotine, leading to an increase in plasma concentration levels of nicotine (Winters et al

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